Oprah and Komodos

I’m easily excited by shows on television about animals–wild ones, of the non-human variety. Programs like “Nature” and “Nova” on PBS are all-time favorites. I was blown away by the HD nature series “Planet Earth” that aired on Discovery Channel a few years ago (co-produced by the BBC and Discovery Channel). “Planet Earth” featured beautiful, groundbreaking video of diverse habitats across the planet. The producers of “Planet Earth” recently unveiled a new nature series, titled “Life,” that premiered last Sunday evening on Discovery Channel, and should be running for several weeks. Highly similar in style to “Planet Earth”, “Life” features stunning videography, crisp editing, and gripping stories to satisfy bio-whores like myself. I highly recommend it, just as long as you don’t mind being lectured on biology by Oprah Winfrey.
For the American version of “Planet Earth”, the producers struck gold with narration–the exceedingly composed, yet just-so tense, buttery smooth voice of Sigourney Weaver. But in the two chapters of “Life” I watched last Sunday, I felt like I was being read a children’s book. Oprah’s voice is too cherubic to convey the severity of, for example, a pack of Komodo dragons devouring a Water Buffalo to the bone in four hours. Don’t ruin this for me Discovery Channel.
The background music was also often unnecessarily over-dramatic, at times sounding like pieces mainstream movies use during transition scenes where time and character emotions quickly evolve in schmaltzy ways. This window dressing is clearly there to impress those who are not already impressed. I guess I appreciate the effort.
The content of “Life,” though, is superb. Life itself is distilled into three central tenets: eat, avoid being eaten, and reproduce. To demonstrate these principles, stories are drawn from many different animals (mammals, reptiles, fish, insects, etc.), and even plants (Venus Flytrap). For example, in introducing reproductive methods of the male stalk-eyed fly, Oprah mentions the “urge to breed”, and that males often have to “earn the right”. For a premature stalk-eyed male fly to become a heavily endowed, mature one, they climb to the top of a plant and then pump up their translucent eye stalks with air bubbles that they engulf, causing their eyes at the ends of the stalks to grow out away from their bodies. The most well-endowed males may then convene to fight, winner gets the female.
Sardines were highlighted for a technique they use to avoid being eaten by swordfish–swimming together in a large school, wholly changing direction rapidly, like a “single organism”, making it harder to pick out individuals.
For an example of the need to eat, the show reprised a wonderful story that was also in the Planet Earth series, the most human-like, showing clever monkeys from central Brazil that use rock tools to crack open nuts they rely on for food. Younger monkeys imitate their elders, unsuccessfully, for up to eight years before they perfect nut cracking.
The segment from last Sunday that dropped my jaw the farthest concerned a hungry Komodo dragon. (Hmm… great name for a heavy metal band.) On an island in Indonesia, the only region in the world these huge lizards are found, it’s dry season. Food’s at a premium. This is no time to be anywhere near a Komodo dragon. The cameramen happen upon a sole Water Buffalo lazily sauntering around an evaporating watering hole. A nearby Komodo seizes its opportunity. At first, the Water Buffalo mostly ignores the lizard, seeing only a nuisance. The Buffalo outsizes the Komodo as an adult human a house cat. But the Komodo needs just one, venomous bite to begin meal preparation. The dragon waits for the perfect moment to sink its teeth into the Buffalo’s leg, wary to avoid a powerful kick that could break it’s jaw or kill it. Once successful, the venom begins to set in very slowly. The Komodo is “focused” and “relentless.” It follows the weakening Buffalo everywhere, continually harassing it. Soon other Komodos follow suit, realizing an imminent meal. The Buffalo lacks sufficient food and water, and its wounds fester. After three weeks, the Buffalo succumbs. Within four hours it’s museum ready, skeletonized. That’s life.

Sarah Palin: Stupid as a melting iceberg
I’m was amused by Sarah Palin’s Op-Ed that appeared in the Washington Post last week. In it she says that most scientists studying climate change are highly politicized, their proposed policies are not based on sound science, and that enacting such policies would acutely weaken the US economy.
Over a year ago, in our local MIT student run newspaper The Tech, I wrote a response to an opinion on the topic of Sarah Palin and her science rhetoric during her notorious vice presidential campaign. In it I said:
Mrs. Palin’s statements concerning science have been outstandingly defective and misinformed, surely causing research scientists, science educators, students of science, and many others to cringe in response. It is a great failure for the scientific community to witness a person making these statements rise to the position of vice presidential candidate.
I’ll add today that I am–and perhaps many other scientists are–still embarrassed to witness a person making these statements possess the fame and resources to publish them in a national newspaper with a readership as wide as the Washington Post’s.
God she’s dumb.
CNN=science journalism pretty not good
In my daily (hourly), incredibly narcissistic practice of reading my own blog (the one you’re reading right now), I traveled back to my October 7th post about how Harry Noller got screwed by being overlooked for the Nobel Prize for work on the ribosome. Below the post, under WordPress’s automatically generated “possibly related posts,” was a link to a CNN article with an amusing, although I suppose technically accurate title:
“Chemistry Nobel honors research on life-giving ribosome”
“Life-giving” ribosome? Ha. Yes. I remember that’s exactly how Harry Noller introduced it to us in Biochem 100A back in college. So next time you say grace/thanks, thank the ribosome for giving you life. Ok?
Following the title is an underwhelming article. At least there’s a nice picture of Tom Steitz sportin’ his trademark frosty chinstrap beard. I’m not making fun–if I could pull that off, I would try. And now with a Nobel in his pocket (around his neck perhaps), that look is certified OG.
Harry Noller got shafted by the 2009 Nobel Prize in Chemistry
“For studies of the structure and function of the ribosome,” the prize was awarded. Why not Harry Noller then, whose entire illustrious career has focused on the structure and function of the ribosome? That’s bullshit.
Unfortunately this egregious omission by the Nobel Assembly pollutes recognition of momentous work that has taught us so much about what RNA can do.
(Santa Cruz Sentinel article with Harry’s reaction here.)
Da Prize
You’ve probably heard the news by now: the 2009 Nobel Prize in Physiology or Medicine was awarded to Elizabeth Blackburn, Carol Greider and Jack Szostak for the discovery of “how chromosomes are protected by telomeres and the enzyme telomerase,” in the words of the Nobel Assembly. Awesome. Congrats to these superb researchers for their smashing work.
An “unsentimental education”
I’ve been thinking about graduate school and mental health recently. Depending on circumstances, working toward a Ph.D. can bring about pressures on the mind strong enough to disturb it. Situations that end in the most extreme outcomes, like suicide, of course can probably never be fully attributed to an experiment gone wrong, an adviser gone wrong, an institution, or impending dismal career prospects. These cases are highly personal; many other people in otherwise identical circumstances would not react the same way. So look out for your chums, and your non-chums/co-workers too.
I was considering writing a piece about mental health among grad students at MIT, although I have now dropped the idea–too close to home I think. But while I was still investing interest in this story, a teacher refered me to an article, by Stephan S. Hall, that appeared in The New York Times Magazine in November, 1998, titled “Lethal Chemistry at Harvard”. It is an excellently written, but nonetheless very sad story about a graduate student in the chemistry department at Harvard who took his life in 1998. In the story, Hall wrote a paragraph describing the archetypal journey of a graduate student in the sciences. I found it so realistic that I think it’s worth reprinting:
Graduate study in the sciences, however, is a very unsentimental education. It requires the intellectual evolution from undergrad who can ace tests of textbook knowledge to original thinker who can initiate and execute research about which the textbooks have yet to be written. What is less often acknowledged is that this intense education involves an equally arduous psychological transition, almost a second rebellious adolescence. The passage from callow, eager-to-please first-year student in awe of an often-famous faculty adviser to confident, independent-minded researcher willing to challenge, and sometimes defy, a mentor is a requisite part of the journey.
I haven’t gotten to the defy your mentor stage yet, but boy I can’t wait. I’ve seen others do it and it looks pretty cool.
Scott Valastyan teaches Bob Weinberg about microRNAs
Led by the sage Scott Valastyan, a graduate student in Bob Weinberg’s laboratory, a new study in the June 12 issue of Cell demonstrates miR-31′s role in inhibiting breast cancer metastasis. Cell’s website recognizes the paper with a video where Bob and Scott are a first-rate scientific tag team:
RNA in NYT
An article published Wednesday in the New York TImes highlights a new Letter in Nature that further bolsters the RNA World hypothesis.
Hmm… time it is to dust off the old organic chemistry textbook from college and make sense of phrases like, (from paper): “…intra-adduct attack of the glycolaldehyde-derived hydroxyl group on the cyanamide-derived nitrile carbon…” Indeed.



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