More evidence of non-boring scientists
Dennis is a cool dude; it’s self-reinforcing in his staff.
Remember, no grant could ever fund this kind of lab environment!
Kim Lab, Department of Biology, MIT
RNA Journal Club 12/15/11
The In Vivo Kinetics of RNA Polymerase II Elongation during Co-Transcriptional Splicing
Yehuda Brody, Noa Neufeld, Nicole Bieberstein, Sebastien Z. Causse, Eva-Maria Böhnlein, Karla M. Neugebauer, Xavier Darzacq, Yaron Shav-Tal
PLoS Biology | Volume 9 | Issue 1 | e1000573 | January 2011
doi:10.1371/journal.pbio.1000573
RNA Journal Club 12/8/11
Single-Molecule Imaging of Transcriptionally Coupled and Uncoupled Splicing
Diana Y. Vargas, Khyati Shah, Mona Batish, Michael Levandoski, Sourav Sinha, Salvatore A.E. Marras, Paul Schedl, and Sanjay Tyagi
Cell 147, 1054–1065, 23 November 2011.
DOI 10.1016/j.cell.2011.10.024
RNA Journal Club 12/1/11
Filippo M. Cernilogar, Maria Cristina Onorati, Greg O. Kothe, A. Maxwell Burroughs, Krishna Mohan Parsi, Achim Breiling, Federica Lo Sardo, Alka Saxena, Keita Miyoshi, Haruhiko Siomi, Mikiko C. Siomi, Piero Carninci, David S. Gilmour, Davide F. V. Corona & Valerio Orlando
Nature AOP, 6 November 2011.
doi:10.1038/nature10492
RNA Journal Club 11/17/11
Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs
Yvonne Tay, Lev Kats, Leonardo Salmena, Dror Weiss, Shen Mynn Tan, Ugo Ala, Florian Karreth, Laura Poliseno, Paolo Provero, Ferdinando Di Cunto, Judy Lieberman, Isidore Rigoutsos, and Pier Paolo Pandolfi
Cell 147, 344–357, 14 October 2011.
DOI 10.1016/j.cell.2011.09.029
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Pavel Sumazin, Xuerui Yang, Hua-Sheng Chiu, Wei-Jen Chung, Archana Iyer, David Llobet-Navas, Presha Rajbhandari, Mukesh Bansal, Paolo Guarnieri, Jose Silva, and Andrea Califano
Cell 147, 370–381, 14 October 2011.
DOI 10.1016/j.cell.2011.09.041
RNA Journal Club 11/10/11
Nicholas T. Ingolia, Liana F. Lareau, and Jonathan S. Weissman
Cell 147, 1–14, 11 November 2011.
DOI 10.1016/j.cell.2011.10.002
RNA Journal Club 11/3/11
Genomic Maps of Long Noncoding RNA Occupancy Reveal Principles of RNA-Chromatin Interactions
Ci Chu, Kun Qu, Franklin L. Zhong, Steven E. Artandi, and Howard Y. Chang
Molecular Cell 44, 1–12, 18 November 2011.
DOI 10.1016/j.molcel.2011.08.027
RNA Journal Club 10/20/11
RNAi promotes heterochromatic silencing through replication-coupled release of RNA Pol II
Mikel Zaratiegui, Stephane E. Castel, Danielle V. Irvine, Anna Kloc, Jie Ren, Fei Li, Elisa de Castro, Laura Marín, An-Yun Chang, Derek Goto, W. Zacheus Cande, Francisco Antequera, Benoit Arcangioli & Robert A. Martienssen
Nature AOP, 16 October 2011.
doi:10.1038/nature10501
Oh No Journal Club 10/13/11
Holy smokes–four back-to-back papers on candy RNAs in today’s Cell?!
(1) Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs
Yvonne Tay, Lev Kats, Leonardo Salmena, Dror Weiss, Shen Mynn Tan, Ugo Ala, Florian Karreth, Laura Poliseno, Paolo Provero, Ferdinando Di Cunto, Judy Lieberman, Isidore Rigoutsos, Pier Paolo Pandolfi
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(2) A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA
Marcella Cesana, Davide Cacchiarelli, Ivano Legnini, Tiziana Santini, Olga Sthandier, Mauro Chinappi, Anna Tramontano, Irene Bozzoni
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(3) An Extensive MicroRNA-Mediated Network of RNA-RNA Interactions Regulates Established Oncogenic Pathways in Glioblastoma
Pavel Sumazin, Xuerui Yang, Hua-Sheng Chiu, Wei-Jen Chung, Archana Iyer, David Llobet-Navas, Presha Rajbhandari, Mukesh Bansal, Paolo Guarnieri, Jose Silva, Andrea Califano
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(4) In Vivo Identification of Tumor- Suppressive PTEN ceRNAs in an Oncogenic BRAF-Induced Mouse Model of Melanoma
Florian A. Karreth, Yvonne Tay, Daniele Perna, Ugo Ala, Shen Mynn Tan, Alistair G. Rust, Gina DeNicola, Kaitlyn A. Webster, Dror Weiss, Pedro A. Perez-Mancera, Michael Krauthammer, Ruth Halaban, Paolo Provero, David J. Adams, David A. Tuveson, Pier Paolo Pandolfi
RNA Journal Club 10/13/11
Cell Adhesion-Dependent Control of MicroRNA Decay
Young-Kook Kim, Jinah Yeo, Minju Ha, Boseon Kim, and V. Narry Kim
Molecular Cell 43, 1005–1014, 16 September 2011.
DOI 10.1016/j.molcel.2011.07.031










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