You'd Prefer An Argonaute

RNA Journal Club 2/23/12

Posted in RNA Journal Club by YPAA on February 23, 2012

DNase I sensitivity QTLs are a major determinant of human expression variation

Jacob F. Degner, Athma A. Pai, Roger Pique-Regi, Jean-Baptiste Veyrieras, Daniel J. Gaffney, Joseph K. Pickrell, Sherryl De Leon, Katelyn Michelini, Noah Lewellen, Gregory E. Crawford, Matthew Stephens, Yoav Gilad & Jonathan K. Pritchard

Nature 482, 390—394, 16 February 2012.
doi:10.1038/nature10808

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RNA Journal Club 2/16/12

Posted in RNA Journal Club by YPAA on February 16, 2012

PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2

Sika Zheng, Erin E Gray, Geetanjali Chawla, Bo Torben Porse, Thomas J O’Dell & Douglas L Black

Nature Neuroscience AOP, 15 January 2012.
doi:10.1038/nn.3026

RNA Journal Club 2/9/12

Posted in RNA Journal Club by YPAA on February 9, 2012

Sperm-borne microRNA-34c is required for the first cleavage division in mouse

Wei-Min Liu, Ronald T. K. Pang, Philip C. N. Chiu, Benancy P. C. Wong, Kaiqin Lao, Kai-Fai Lee, and William S. B. Yeung

PNAS vol. 109, no. 2, 490–494, 10 January 2012.
doi: 10.1073/pnas.1110368109

RNA Journal Club 2/2/12

Posted in RNA Journal Club by YPAA on February 2, 2012

Murine cytomegalovirus encodes a miR-27 inhibitor disguised as a target

Valentina Libri, Aleksandra Helwak, Pascal Miesen, Diwakar Santhakumar, Jessica G. Borger, Grzegorz Kudla, Finn Grey, David Tollervey, and Amy H. Buck

PNAS vol. 109, no. 1, 279–284, 3 January 2012.
doi: 10.1073/pnas.1114204109

RNA Journal Club 1/26/12

Posted in RNA Journal Club by YPAA on January 26, 2012

Decapping of Long Noncoding RNAs Regulates Inducible Genes

Sarah Geisler, Lisa Lojek, Ahmad M. Khalil, Kristian E. Baker, and Jeff Coller

Molecular Cell 45, 1–13, 10 February 2012.
DOI 10.1016/j.molcel.2011.11.025

RNA Journal Club 1/19/12

Posted in RNA Journal Club by YPAA on January 19, 2012

Cap-Assisted Internal Initiation of Translation of Histone H4

Franck Martin, Sharief Barends, Sophie Jaeger, Laure Schaeffer, Lydia Prongidi-Fix, and Gilbert Eriani

Molecular Cell 41, 197–209, 21 January 2011.
DOI 10.1016/j.molcel.2010.12.019

RNA Journal Club 1/12/12

Posted in RNA Journal Club by YPAA on January 12, 2012

Adaptation to P Element Transposon Invasion in Drosophila melanogaster

Jaspreet S. Khurana, Jie Wang, Jia Xu, Birgit S. Koppetsch, Travis C. Thomson, Anetta Nowosielska, Chengjian Li, Phillip D. Zamore, Zhiping Weng, and William E. Theurkauf

Cell 147, 1551–1563, 23 December 2011.
DOI 10.1016/j.cell.2011.11.042

RNA Journal Club 1/5/12

Posted in RNA Journal Club by YPAA on January 5, 2012

Selective Ribosome Profiling Reveals the Cotranslational Chaperone Action of Trigger Factor In Vivo

Eugene Oh, Annemarie H. Becker, Arzu Sandikci, Damon Huber, Rachna Chaba, Felix Gloge, Robert J. Nichols, Athanasios Typas, Carol A. Gross, Günter Kramer, Jonathan S. Weissman, and Bernd Bukau

Cell 147, 1295–1308, 9 December 2011.
DOI 10.1016/j.cell.2011.10.044

RNA Journal Club 12/15/11

Posted in RNA Journal Club by YPAA on December 15, 2011

The In Vivo Kinetics of RNA Polymerase II Elongation during Co-Transcriptional Splicing

Yehuda Brody, Noa Neufeld, Nicole Bieberstein, Sebastien Z. Causse, Eva-Maria Böhnlein, Karla M. Neugebauer, Xavier Darzacq, Yaron Shav-Tal

PLoS Biology | Volume 9 | Issue 1 | e1000573 | January 2011
doi:10.1371/journal.pbio.1000573

RNA Journal Club 12/8/11

Posted in RNA Journal Club by YPAA on December 8, 2011

Single-Molecule Imaging of Transcriptionally Coupled and Uncoupled Splicing

Diana Y. Vargas, Khyati Shah, Mona Batish, Michael Levandoski, Sourav Sinha, Salvatore A.E. Marras, Paul Schedl, and Sanjay Tyagi

Cell 147, 1054–1065, 23 November 2011.
DOI 10.1016/j.cell.2011.10.024

RNA Journal Club 12/1/11

Posted in RNA Journal Club by YPAA on December 1, 2011

Chromatin-associated RNA interference components contribute to transcriptional regulation in Drosophila

Filippo M. Cernilogar, Maria Cristina Onorati, Greg O. Kothe, A. Maxwell Burroughs, Krishna Mohan Parsi, Achim Breiling, Federica Lo Sardo, Alka Saxena, Keita Miyoshi, Haruhiko Siomi, Mikiko C. Siomi, Piero Carninci, David S. Gilmour, Davide F. V. Corona & Valerio Orlando

Nature AOP, 6 November 2011.
doi:10.1038/nature10492

RNA Journal Club 11/17/11

Posted in RNA Journal Club by YPAA on November 17, 2011

Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs

Yvonne Tay, Lev Kats, Leonardo Salmena, Dror Weiss, Shen Mynn Tan, Ugo Ala, Florian Karreth, Laura Poliseno, Paolo Provero, Ferdinando Di Cunto, Judy Lieberman, Isidore Rigoutsos, and Pier Paolo Pandolfi

Cell 147, 344–357, 14 October 2011.
DOI 10.1016/j.cell.2011.09.029

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An Extensive MicroRNA-Mediated Networkof RNA-RNA Interactions Regulates Established Oncogenic Pathways in Glioblastoma

Pavel Sumazin, Xuerui Yang, Hua-Sheng Chiu, Wei-Jen Chung, Archana Iyer, David Llobet-Navas, Presha Rajbhandari, Mukesh Bansal, Paolo Guarnieri, Jose Silva, and Andrea Califano

Cell 147, 370–381, 14 October 2011.
DOI 10.1016/j.cell.2011.09.041

RNA Journal Club 11/10/11

Posted in RNA Journal Club by YPAA on November 10, 2011

Ribosome Profiling of Mouse Embryonic Stem Cells Reveals the Complexity and Dynamics of Mammalian Proteomes

Nicholas T. Ingolia, Liana F. Lareau, and Jonathan S. Weissman

Cell 147, 1–14, 11 November 2011.
DOI 10.1016/j.cell.2011.10.002