You'd Prefer An Argonaute

~ Intermission ~

Posted in Blog Affairs by YPAA on March 1, 2012

Cabot Street Cinema, Massachusetts by Hiroshi Sugimoto

This isn’t necessarily the final post for You’d Prefer An Argonaute, but I’m calling an intermission, or hitting the standby button perhaps.

While I’ve thoroughly enjoyed running the blog the past three years, other priorities have taken hold of me, and the blog is getting sleepy, so to speak.

There haven’t been contributions to the RNA Journal Club posts for quite a while. When even I didn’t find the time to do one for my last presentation, it got harder for me to in fair conscience ask others to still contribute. I don’t see a point in continuing to post the papers weekly now that there are no more reviews.

I am extremely grateful to the following people who did contribute: Vikram Agarwal, Josh Arribere, Graeme Doran, Anna Drinnenberg, Robin Friedman, Huili Guo, Allan Gurtan, Mohini Jangi, Carla Klattenhoff, David Koppstein, Madhu Kumar, Charles Lin, Joel Neilson, Michael Nodine, Alex Robertson, Jenny Rood, Noah Spies, Alex Subtelny, Igor Ulitsky, Pavan Vaidyanathan, David Weinberg, Josien van Wolfswinkel, Xuebing Wu, and Muhammed Yildirim.

Pretty much all these people are going to be successful P.I.’s/scientists one day. There’s a significant correlation I tell you!

I hope to still post periodically, things like the annual lists of RNA conferences I compile. And maybe the blog will get its second wind during my postdoc… we’ll see. In the meantime don’t fret about the site disappearing from the web, however, the URL could change if I get sick of paying rent on the domain.

Sometimes I feel like I’ve been writing for an alien audience, because I’ve had practically no contact with viewers. Who and what are you? Spam drones? Bored teenagers?

Well, to the curious, nerdy aliens who landed here for knowledge or laughs, thanks for reading, and stay true in your science.

boESCs

Posted in Gallimaufry, Lab Life by YPAA on February 29, 2012

OKAY, OKAY.  But where can we get some ObamaESCs?  At least something to reprogram?  We gotta clone that mofo.

RNA Journal Club 2/23/12

Posted in RNA Journal Club by YPAA on February 23, 2012

DNase I sensitivity QTLs are a major determinant of human expression variation

Jacob F. Degner, Athma A. Pai, Roger Pique-Regi, Jean-Baptiste Veyrieras, Daniel J. Gaffney, Joseph K. Pickrell, Sherryl De Leon, Katelyn Michelini, Noah Lewellen, Gregory E. Crawford, Matthew Stephens, Yoav Gilad & Jonathan K. Pritchard

Nature 482, 390—394, 16 February 2012.
doi:10.1038/nature10808

RNA Journal Club 2/16/12

Posted in RNA Journal Club by YPAA on February 16, 2012

PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2

Sika Zheng, Erin E Gray, Geetanjali Chawla, Bo Torben Porse, Thomas J O’Dell & Douglas L Black

Nature Neuroscience AOP, 15 January 2012.
doi:10.1038/nn.3026

RNA Journal Club 2/9/12

Posted in RNA Journal Club by YPAA on February 9, 2012

Sperm-borne microRNA-34c is required for the first cleavage division in mouse

Wei-Min Liu, Ronald T. K. Pang, Philip C. N. Chiu, Benancy P. C. Wong, Kaiqin Lao, Kai-Fai Lee, and William S. B. Yeung

PNAS vol. 109, no. 2, 490–494, 10 January 2012.
doi: 10.1073/pnas.1110368109

RNA Journal Club 2/2/12

Posted in RNA Journal Club by YPAA on February 2, 2012

Murine cytomegalovirus encodes a miR-27 inhibitor disguised as a target

Valentina Libri, Aleksandra Helwak, Pascal Miesen, Diwakar Santhakumar, Jessica G. Borger, Grzegorz Kudla, Finn Grey, David Tollervey, and Amy H. Buck

PNAS vol. 109, no. 1, 279–284, 3 January 2012.
doi: 10.1073/pnas.1114204109

iBioSeminars: RNA

Posted in Media, Talks by YPAA on January 29, 2012

Roy Parker Part 1: Mechanisms and Control of mRNA Localization, Translation and Degradation

blank

blank

Roy Parker Part 2: P-bodies and the mRNA Cycle

blank

blank

Melissa Moore Part 1: Split Genes and RNA Splicing

blank

blank

Melissa Moore Part 2: Spliceosome Structure and Dynamics

blank

blank

Ruth Lehmann Part 2: RNA Regulation

blank

blank

Jack Szostak Part 1: The Origin of Cellular Life on Earth

blank

blank

Jack Szostak Part 3: Non-enzymatic Copying of Nucleic Acid Templates

blank

Lectures from ibioseminars.org.

RNA Journal Club 1/26/12

Posted in RNA Journal Club by YPAA on January 26, 2012

Decapping of Long Noncoding RNAs Regulates Inducible Genes

Sarah Geisler, Lisa Lojek, Ahmad M. Khalil, Kristian E. Baker, and Jeff Coller

Molecular Cell 45, 1–13, 10 February 2012.
DOI 10.1016/j.molcel.2011.11.025

RNA Journal Club 1/19/12

Posted in RNA Journal Club by YPAA on January 19, 2012

Cap-Assisted Internal Initiation of Translation of Histone H4

Franck Martin, Sharief Barends, Sophie Jaeger, Laure Schaeffer, Lydia Prongidi-Fix, and Gilbert Eriani

Molecular Cell 41, 197–209, 21 January 2011.
DOI 10.1016/j.molcel.2010.12.019

RNAi video animation

Posted in Media by YPAA on January 15, 2012

RNA Journal Club 1/12/12

Posted in RNA Journal Club by YPAA on January 12, 2012

Adaptation to P Element Transposon Invasion in Drosophila melanogaster

Jaspreet S. Khurana, Jie Wang, Jia Xu, Birgit S. Koppetsch, Travis C. Thomson, Anetta Nowosielska, Chengjian Li, Phillip D. Zamore, Zhiping Weng, and William E. Theurkauf

Cell 147, 1551–1563, 23 December 2011.
DOI 10.1016/j.cell.2011.11.042

RNA Journal Club 1/5/12

Posted in RNA Journal Club by YPAA on January 5, 2012

Selective Ribosome Profiling Reveals the Cotranslational Chaperone Action of Trigger Factor In Vivo

Eugene Oh, Annemarie H. Becker, Arzu Sandikci, Damon Huber, Rachna Chaba, Felix Gloge, Robert J. Nichols, Athanasios Typas, Carol A. Gross, Günter Kramer, Jonathan S. Weissman, and Bernd Bukau

Cell 147, 1295–1308, 9 December 2011.
DOI 10.1016/j.cell.2011.10.044

Cell Club 12/23/11

Posted in Evolution, Media by YPAA on December 23, 2011

Cell made a paperflick about a new study uncovering mechanisms of silencing of new transposons by piRNAs, from Bill Theurkauf and colleagues.

Follow

Get every new post delivered to your Inbox.