~ Intermission ~

Cabot Street Cinema, Massachusetts by Hiroshi Sugimoto
This isn’t necessarily the final post for You’d Prefer An Argonaute, but I’m calling an intermission, or hitting the standby button perhaps.
While I’ve thoroughly enjoyed running the blog the past three years, other priorities have taken hold of me, and the blog is getting sleepy, so to speak.
There haven’t been contributions to the RNA Journal Club posts for quite a while. When even I didn’t find the time to do one for my last presentation, it got harder for me to in fair conscience ask others to still contribute. I don’t see a point in continuing to post the papers weekly now that there are no more reviews.
I am extremely grateful to the following people who did contribute: Vikram Agarwal, Josh Arribere, Graeme Doran, Anna Drinnenberg, Robin Friedman, Huili Guo, Allan Gurtan, Mohini Jangi, Carla Klattenhoff, David Koppstein, Madhu Kumar, Charles Lin, Joel Neilson, Michael Nodine, Alex Robertson, Jenny Rood, Noah Spies, Alex Subtelny, Igor Ulitsky, Pavan Vaidyanathan, David Weinberg, Josien van Wolfswinkel, Xuebing Wu, and Muhammed Yildirim.
Pretty much all these people are going to be successful P.I.’s/scientists one day. There’s a significant correlation I tell you!
I hope to still post periodically, things like the annual lists of RNA conferences I compile. And maybe the blog will get its second wind during my postdoc… we’ll see. In the meantime don’t fret about the site disappearing from the web, however, the URL could change if I get sick of paying rent on the domain.
Sometimes I feel like I’ve been writing for an alien audience, because I’ve had practically no contact with viewers. Who and what are you? Spam drones? Bored teenagers?
Well, to the curious, nerdy aliens who landed here for knowledge or laughs, thanks for reading, and stay true in your science.
boESCs

OKAY, OKAY. But where can we get some ObamaESCs? At least something to reprogram? We gotta clone that mofo.
RNA Journal Club 2/23/12
DNase I sensitivity QTLs are a major determinant of human expression variation
Jacob F. Degner, Athma A. Pai, Roger Pique-Regi, Jean-Baptiste Veyrieras, Daniel J. Gaffney, Joseph K. Pickrell, Sherryl De Leon, Katelyn Michelini, Noah Lewellen, Gregory E. Crawford, Matthew Stephens, Yoav Gilad & Jonathan K. Pritchard
Nature 482, 390—394, 16 February 2012.
doi:10.1038/nature10808
RNA Journal Club 2/16/12
PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2
Sika Zheng, Erin E Gray, Geetanjali Chawla, Bo Torben Porse, Thomas J O’Dell & Douglas L Black
Nature Neuroscience AOP, 15 January 2012.
doi:10.1038/nn.3026
RNA Journal Club 2/9/12
Sperm-borne microRNA-34c is required for the first cleavage division in mouse
Wei-Min Liu, Ronald T. K. Pang, Philip C. N. Chiu, Benancy P. C. Wong, Kaiqin Lao, Kai-Fai Lee, and William S. B. Yeung
PNAS vol. 109, no. 2, 490–494, 10 January 2012.
doi: 10.1073/pnas.1110368109
RNA Journal Club 2/2/12
Murine cytomegalovirus encodes a miR-27 inhibitor disguised as a target
Valentina Libri, Aleksandra Helwak, Pascal Miesen, Diwakar Santhakumar, Jessica G. Borger, Grzegorz Kudla, Finn Grey, David Tollervey, and Amy H. Buck
PNAS vol. 109, no. 1, 279–284, 3 January 2012.
doi: 10.1073/pnas.1114204109
iBioSeminars: RNA
Roy Parker Part 1: Mechanisms and Control of mRNA Localization, Translation and Degradation
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Roy Parker Part 2: P-bodies and the mRNA Cycle
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Melissa Moore Part 1: Split Genes and RNA Splicing
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Melissa Moore Part 2: Spliceosome Structure and Dynamics
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Ruth Lehmann Part 2: RNA Regulation
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Jack Szostak Part 1: The Origin of Cellular Life on Earth
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Jack Szostak Part 3: Non-enzymatic Copying of Nucleic Acid Templates
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Lectures from ibioseminars.org.
RNA Journal Club 1/26/12
Decapping of Long Noncoding RNAs Regulates Inducible Genes
Sarah Geisler, Lisa Lojek, Ahmad M. Khalil, Kristian E. Baker, and Jeff Coller
Molecular Cell 45, 1–13, 10 February 2012.
DOI 10.1016/j.molcel.2011.11.025
RNA Journal Club 1/19/12
Cap-Assisted Internal Initiation of Translation of Histone H4
Franck Martin, Sharief Barends, Sophie Jaeger, Laure Schaeffer, Lydia Prongidi-Fix, and Gilbert Eriani
Molecular Cell 41, 197–209, 21 January 2011.
DOI 10.1016/j.molcel.2010.12.019
RNA Journal Club 1/12/12
Adaptation to P Element Transposon Invasion in Drosophila melanogaster
Jaspreet S. Khurana, Jie Wang, Jia Xu, Birgit S. Koppetsch, Travis C. Thomson, Anetta Nowosielska, Chengjian Li, Phillip D. Zamore, Zhiping Weng, and William E. Theurkauf
Cell 147, 1551–1563, 23 December 2011.
DOI 10.1016/j.cell.2011.11.042
RNA Journal Club 1/5/12
Selective Ribosome Profiling Reveals the Cotranslational Chaperone Action of Trigger Factor In Vivo
Eugene Oh, Annemarie H. Becker, Arzu Sandikci, Damon Huber, Rachna Chaba, Felix Gloge, Robert J. Nichols, Athanasios Typas, Carol A. Gross, Günter Kramer, Jonathan S. Weissman, and Bernd Bukau
Cell 147, 1295–1308, 9 December 2011.
DOI 10.1016/j.cell.2011.10.044
Cell Club 12/23/11
Cell made a paperflick about a new study uncovering mechanisms of silencing of new transposons by piRNAs, from Bill Theurkauf and colleagues.

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